Biome-Balancing Clear & Prevent Blemish Treatment Serum

Size
  • 30ML

MICROBIOME-BALANCING BLEMISH TREATMENT THAT HELPS CLEAR HORMONAL BREAKOUTS, REDUCE CONGESTION AND SUPPORT A HEALTHY SKIN BARRIER WITHOUT OVER-DRYING SKIN.

 

  • Specifically formulated for hormonally ageing skin to clear and help prevent breakouts without over-drying.
  • Biome-Sensing Technology and glutamic acid support a balanced microbiome and stronger skin barrier.
  • Salicylic acid and mandelic acid unclog pores, reduce blemishes and smooth skin texture.
  • Non-comedogenic, non-drying and gentle enough for daily use, even on sensitive skin.
SKU: 81128

Clearer skin starts in just 3 days*

DETAILS

Getting skin clear is all about breakouts. Keeping it clear is all about a balanced microbiome. Get the best of both worlds with Murad's latest innovation that works as hard to clear breakouts as it does to keep your skin microbiome balanced. We merged trusted breakout-clearing ingredients like salicylic acid with breakthrough Biome-Sensing Tech that encourage a healthier, more balanced microbiome that's naturally more resistant to future breakouts—and that means smoother, clearer skin for the long run

*Consumer testing on 26 subjects in an 8-week study

Which skin type is it good for?
  • Balanced·
  • Oily·
  • Combination
Results

Unretouched real results

  • Clinically proven to deliver clearer, healthier-looking skin*
  • Clinically proven to reduce active breakouts*
  • Clearer skin starts in 3 days†



92% agree: no unwanted side effects†:

  • peeling 
  • flaking 
  • redness 
  • irritation



*Expert grading of photos on 26 subjects in an 8-week study 
†Consumer testing on 26 subjects in an 8-week study

INGREDIENTS

Expert, science-backed ingredients and patented technologies

CLINICAL NOTE

Why stop at clear skin? Our new Blemish Serum not only treats and prevents breakouts, but also “feeds” good bacteria that empowers your microbiome to thrive—for balanced, healthier-looking skin

How To

To Use: AM and PM

Get the Facts

  • Big zit, now what? How to get rid of acne fast

    Whether it’s the night before a date or you’re preparing for a potentially career-changing meeting in the morning, it never fails. Learn More
  • How to create the best skincare routine for blemish-prone skin

    Because acne treatment isn’t one size fits all. Learn More

Frequently Asked Questions

1.0% salicylic acid, mandelic acid, glutamic acid, and Biome-Sensing Tech.

Hormonal fluctuations can increase oil production and contribute to congestion, particularly around the jawline, chin and lower face. These changes can trigger breakouts even if you haven't experienced acne in years.

Yes. Biome-Balancing Clear & Prevent Blemish Treatment is designed to help reduce blemishes and support clearer-looking skin while helping maintain a healthy skin barrier and microbiome.

Hormonal acne is often concentrated around the jawline, chin and lower face and can occur alongside dryness, sensitivity and visible signs of ageing. Teenage acne is typically associated with excess oil production and congestion across the T-zone.

Yes. Unlike many traditional acne treatments, this formula is designed to help support the skin barrier and microbiome while targeting blemishes, making it suitable for adult skin experiencing hormonal changes.

Jawline and chin breakouts are commonly associated with hormonal fluctuations. Changes in androgen levels can stimulate excess oil production in these areas, increasing the likelihood of congestion and blemishes.

Yes. Regular use helps support a balanced skin environment while reducing factors that contribute to recurring blemishes and congestion.

The skin microbiome is a community of beneficial microorganisms that help support healthy skin. When the microbiome becomes unbalanced, skin may be more prone to breakouts, irritation and sensitivity.

Yes. Many women experience both visible signs of ageing and breakouts during perimenopause and menopause. This product is designed to help address blemishes without compromising skin comfort.

Acne-prone skin and those with mild-to-moderate breakouts, plus anyone wanting to improve uneven texture or tone.

Apply to clean skin morning and/or night. Use all-over or as a spot treatment. Allow to dry, then layer moisturizer and makeup as desired.

It's formulated to be non-drying and non-irritating and many users find it gentle, but individual reactions can vary.

Gel-serum: lightweight, slightly tacky on application, absorbs quickly. Minimal to no scent; some users note a faint floral note.

Yes. The formula layers well under makeup for most users and is reported to avoid pilling.

The formula contains salicylic acid at 1.0%.

Clinical testing was performed on those with mild-moderate acne. For deep, painful bumps and blemishes, we recommend Deep Relief Blemish Treatment.

This serum clears all types of breakouts, from whiteheads to hormonal acne. And it prevents relapses using salicylic acid, mandelic acid, Biome-Sensing Tech, and glutamic acid to balance the skin's microbiome for healthier-looking skin.

Apply 1-2 pumps of the serum to clean face and neck. Let it dry completely before applying moisturiser, SPF, or makeup.

Yes, but do not layer. Rather, use Biome-Balancing Blemish Treatment Serum in the morning and Deep Relief Blemish Treatment at night.

The serum works for balanced, oily, and combination skin types.

It's clinically proven to deliver clearer, healthier-looking skin and reduce active breakouts, with clearer skin starting in just 3 days based on consumer testing.

Yes, it's non-irritating, non-drying, and gentle enough for daily use, with clinical results showing no redness, peeling, flaking, or irritation in testing.

Unlike typical treatments, it not only clears breakouts with proven actives but also uses Biome-Sensing Tech and glutamic acid to empower the microbiome against future breakouts for long-term smoother, clearer skin.

Yes, it's gentle enough for daily use, non-comedogenic, non-drying, and layers well under makeup without pilling or flaking.

Yes. This treatment can be incorporated into a routine alongside retinol or retinal products. Supporting the skin barrier is especially important when using active ingredients in hormonally ageing skin.

For hormonally ageing, blemish-prone skin, pair with: AHA/BHA Exfoliating Cleanser, Cellular Hydration Barrier Repair Serum, Nutrient-Charged Water Gel, Retinol Youth Renewal Serum (PM). These combinations help support clearer, balanced skin while addressing hydration, barrier health and visible signs of ageing.

Overall rating: 4.7777777 / 5 from 9 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["breakouts","skin"].

Review highlights

Reviews

This product has genuinely changed my life

"There is no skincare product that I’ve ever used which has made more of a positive impact on my skin. I have dry and sensitive eczema prone skin so I’ve always been mostly focused on hydrating my skin but lately I’ve been getting breakouts too. This product not only has got rid of my breakouts but it has also improved my skin hydration to no end. I don’t know what they put in this but literally give it to me daily for the rest of my life please. Do I start stockpiling? 😂"

Rosie M. (5/5)

Clear Skin Win: Serum That Really works!

"My son recently took part in the Murad 3-week trial, and the results were amazing. We saw such a big difference in his skin in just three weeks. He’s tried other serums from different brands before, but this is the first one that really worked for him. His face looks so much clearer and healthier, and we couldn’t be happier. I’d definitely recommend this product."

Kristy (5/5)

Focus on Results

"This serum made a big difference in reducing my blemishes and redness. Within a few days, my skin started to look clearer and less oily around the T-zone. It’s gentle enough for daily use, and I love that it keeps my skin hydrated while fighting breakouts. Definitely one of my favourite Murad products!"

Kelly B. (5/5)

A Travel Essential – No More Breakouts!

"Must try. I used to get breakouts from water changes whenever I traveled, but this product has completely changed that! I used it before my recent trip, and for the first time, I didn’t experience any breakouts. It really helped protect my skin and kept it clear the whole time. Highly recommend it if you’re prone to breakouts when traveling!"

Rachel T. (5/5)

Clear skin saver

"I’ve been using this product consistently, and it’s been a game-changer. It kept my blemishes away and helped maintain a smooth, clear complexion. I noticed fewer breakouts and my skin looks healthier overall. Definitely a must-have in my skincare routine!"

Jan (4/5)

Excellent product, kept my breakouts to a minimum.

"I was a part of the skincare trial for this product and have been using it consistently for 3 weeks alongside the clarifying cream cleanser and the clarifying water gel. I suffer from painful, persistent nodular/cystic acne and I found that this product kept my breakouts to a minimum and helped make my skin smooth and soft. I also found that it somewhat improved discolouration on my face from past breakouts. (before photos on the left, after photos on the right)"

Lily (4/5)

Acne be gone

"Superstar product and relief for acne."

Utah B. (5/5)

Im 64 and now have the right skin care products.

"Being 64 yeqrs and having acne issues since my teens, I thought the consistency of my skin - well, is just as it is. Ive had acne it seems forever !!!! There is a newness, a consistent colour and my skin screams - clean. Enlarged pores, lots of acne scarring, black and white heads, even after using various brands to try to correct it. But they never worked. Now for trying the acne cleanser an serum everyday, I hope this isnt a comment that seems outlandish, but the scars were making nasty pimples under the scars, and more trauma to the area to clear the area. Bur Now !!! I came into the with a wide view, hoping it would do as you said. Its the best outcome Ive seen. Any pimples that come up, I just put a dab of the blemish serum, and the redness has reduced and been sent packing to heal. It seems the years of scarring have been evaporated away, and the blockages from closed pores under the scars, (which is really hard to clean) have now gone. I did find that after 2 weeks of regular use, I needed to reduce use of the blue products and just went back to your other brilliant retinol green products. Im using the purple now, I love a mask to leave on overnight, and your purple mask and face cream felt beautiful this morning. In the past, the appearance of my skin in years past, determined my social life, and I am so grateful that my skin now appears less scarred, clear, healthy and gleams."

Sue F. (5/5)

Amazing

"worth buying"

Mehak (5/5)

Q&A